Rapid and direct quantification of the SARS-CoV-2 virus with an ultrasensitive nanobody-based photonic nanosensor
نویسندگان
چکیده
An innovative nanophotonic sensor using bioengineered nanobodies as receptors enables ultrasensitive COVID-19 detection and viral load determination in a 15 min assay without sample pretreatments.
منابع مشابه
SARS-COV-2 Virus; Immune Responses and The Immunopathogenesis
Abstract Background and Objectives Clinical features of SARS-COV-2 virus include fever, headache, cough, sore throat, and shortness of breath, and in severe forms it leads to disseminated intravascular coagulation, septic shock, and ultimately death. Excessive secretion of proinflammatory cytokines such as TNF-α, IL-6, and IL-1 leads to cytokine storms in this disease. The emergence of new va...
متن کاملIntroducing the SARS-CoV-2 and discussing the possible origin of the virus
The emergence of the dangerous and deadly COVID-19 disease in late 2019 in Wuhan, China, and its rapid spread has had a profound global impact on health, mental security, the economy, culture and politics of various countries, drawing the attention of the medical community and related sciences for identification and treatment of this disease. Various studies on the disease have identified a new...
متن کاملCHALLENGES OF LABORATORY SAMPLING AND DIAGNOSIS OF SARS-COV-2 VIRUS OF DISEASE (COVID-19)
Background & Aims: Given the prevalence of SARS-CoV-2 worldwide, it is essential to identify people infected with the virus and determine its different types to control the global outbreak of COVID-19. The results of the studies are controversial, so this study examines these diagnostic challenges, including the types of diagnostic methods, the type and time of sampling, and even the clinical c...
متن کاملInvestigating the Mechanism of Action of SARS-CoV-2 Virus for Drug Designing: A Review
Coronavirus Disease 2019 (COVID-19) is a viral pneumonia emerged in December 2019 in Wuhan, China. Its cause is a new virus from the coronavirus family scientifically named Coronavirus Acute Respiratory Syndrome 2 (SARS-CoV-2). In this review study, articles published in English until March 23, 2020 on new coronavirus infection were reviewed. These articles are obtained by searching in PubMed, ...
متن کاملPhysical Activity and Natural Products and Minerals in the SARS-CoV-2 Pandemic: An Update
Coronavirus-disease 19 (COVID-19) has rapidly become a global public health issue, and there is a desperate need for strategies of prevention, reduction, and treatment to halt the epidemic. The coronavirus affects the immune system, and individuals with a compromised immune system, such as those with diabetes, hypertension, obesity, are more susceptible to this virus. Lifestyle-related variable...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Sensors & diagnostics
سال: 2022
ISSN: ['2635-0998']
DOI: https://doi.org/10.1039/d2sd00082b